Are Saponins in Quinoa Toxic?

Some worry that saponins in quinoa can damage your intestines. But is there evidence to support these claims? 

Monica Reinagel, MS, LD/N, CNS
3-minute read
Episode #393

Saponins from quinoa and other plants have been found to have a number of beneficial properties such as binding to cholesterol, neutralizing free radicals, reducing inflammation, and inhibiting the growth of cancer cells. There’s even talk about quinoa as a potential weight loss aid.

Could Quinoa Promote Weight Loss?

A series of studies done on rats, chickens, and piglets found that diets high in quinoa saponins seemed to keep animals from gaining as much weight as they otherwise would. Part of this may have been because the bitter taste of the saponins reduced the amount of food that the animals ate. Something in the quinoa also seemed to increase the secretion of gut hormones that signal satiety or fullness. It’s also possible that the saponins could suppress growth in animals by interfering with intestinal function or nutrient absorption.

However, the studies were done using very high concentrations of saponins.I think the potential for quinoa to promote weight loss (or intestinal damage!) in humans is limited—because the amount of saponins we’re exposed to is relatively small.

The amount of saponins you'd get by eating quinoa is generally much too small to cause any problems.

Saponins are most concentrated in the leaves of the quinoa plant, which we don’t generally eat, as well as on the surface of the grains. The saponins are readily removed by rinsing the grains before you cook them—a lot of brands are pre-washed to save you this step. And much of the quinoa for sale today has been bred to be lower in saponins to begin with, because it gives the grain a sweeter mellower taste and saves you the trouble of pre-washing it. Saponins do not seem to be further reduced by cooking.

Can Saponins Damage Your Intestines?

The amount of saponins you'd get by eating quinoa is generally much too small to cause any problems. However, if you have some other sort of intestinal issues going on, such as irritable bowel syndrome, where your intestines are already inflamed or irritated, it’s theoretically possible that even a very small amount of saponins could further irritate it.

But if you are generally healthy and eating quinoa doesn’t cause any noticeable problems, I don’t think that you need to worry about your quinoa is secretly poisoning you. It is however another great reminder of the value of eating a varied diet rather than eating the same few super foods every day. Eating a variety of fresh foods helps ensure that you’re getting a broad spectrum of nutrients and phytocompounds. It’s also an easy way to avoid over-exposure to a potential hazard.

If you’re eating quinoa several times a week, why not mix things up a bit? Try some other grains like millet, sorghum, farro, or black rice? There are so many fun and interesting whole grains to try, each with unique nutritional highlights. Here’s a Pinterest board I created with a few of my favorite grain-based salad recipes. If you have others that you like, send me the links and I'll pin them as well!


About the Author

Monica Reinagel, MS, LD/N, CNS

Monica Reinagel is a board-certified licensed nutritionist, author, and the creator of one of iTunes' most highly ranked health and fitness podcasts. Her advice is regularly featured on the TODAY show, Dr. Oz, NPR, and in the nation's leading newspapers, magazines, and websites. Do you have a nutrition question? Call the Nutrition Diva listener line at 443-961-6206. Your question could be featured on the show.