The Controversy Over Testosterone Supplements

Testosterone use has become quite the fad these days, but is it effective? What are its associated risks? Who should actually be prescribed testosterone? The House Call Doctor examines the hoopla over the hormone.

Sanaz Majd, MD
4-minute read
Episode #161

Have you heard?  Testosterone use has become quite the raging fad these days, with men of all ages seeking a prescription for the hormone to treat seemingly everything under the sun, from fatigue and depression to weight gain.

Thanks, in large part, to the ever-powerful media’s brainwashing effects, and the barrage of skewed ads from fortune-hungry pharmaceutical companies, men as young as in their 20’s are Googling their symptoms in search of a “cure” for their depression, while middle-aged men reminiscing about their virile youth are turning to testosterone in hopes of reclaiming their stamina and libido.

These not-so-well-intentioned advertisements on TV have even coined the catchy term, “low T,” while attempting to offer what they’d like to portray as "the fountain of youth."  The pharmaceutical companies spend billions (yes, that’s with a “b”) each year marketing these drugs to the average consumer, attempting to convince them that this “low T” craze is the answer to the normal aging process--all with the purpose of selling their outrageously over-priced drugs, of course.

But is testosterone supplementation really the answer? 

Recent studies have found a possible link to the use of testosterone and heart disease (the number 1 killer of both men and women in the U.S.), and as a result, the FDA has since issued a warning on the use of testosterone, while it researches the data. So certainly, testosterone has its potential risks, and isn’t for everyone. There may be a small subset of patients that it can be appropriate for – but who?

Let’s dissect this rather controversial medical topic in today's episode.

What Is Hypogonadism?

The term "hypogonadism" is one that doctors often use to diagnose patients when prescribing testosterone supplementation. "Hypo" means “low,” and “gonads” refers to the sperm-producing organs in men, or the testes. Therefore, for our purposes today, the medical diagnosis of "hypogonadism" simply refers to testes that don’t produce enough testosterone.

As men age, their testosterone levels naturally and normally decline – the same occurs with women and estrogen. As this normal aging physiologic pattern pans out, it occasionally places men at risk for some complications of hypogonadism, including:

Other more common symptoms--including fatigue, depression, decreased muscle mass and increased fat mass--are often more complex, and are not always attributed to low testosterone levels.  Sure, using testosterone may contribute to improving those frustrating symptoms, but it can be simply a “mask,” without addressing any other underlying health issues (such as anxiety, depression, inactive lifestyle, poor nutrition, etc.)


Please note that all content here is strictly for informational purposes only. This content does not substitute any medical advice, and does not replace any medical judgment or reasoning by your own personal health provider. Please always seek a licensed physician in your area regarding all health related questions and issues.

About the Author

Sanaz Majd, MD

Dr. Sanaz Majd is a board-certified Family Medicine physician who graduated from Drexel University College of Medicine in Philadelphia. Her special interests are women's health and patient education.